SUSPECTED ACID-BASE DISTURBANCE Suspected Acid-Base Disorder Normal pHAcidemia (pH < 7.35) Respiratory Acidosis (pCO2 > 40 mmHg) Methanol Uremia Diabetic Ketoacidosis Propylene Glycol Isoniazid Lactic Acidosis Ethylene Glycol Acetylsalicylic Acid Metabolic Acidosis (HCO3 < 24mmol/L) HCO3 : CO210:10 Renal Gastrointestinal (diarrhea) Alkalemia (pH > 7.45) Metabolic Alkalosis (HCO3 > 28mmol/L) HCO3 : CO212:10 Respiratory Alkalosis (pCO2 < 35 mmHg) Normal Arterial Blood GasMixed Acid-Base Disorder Anion GapNon-Anion GapAcuteHCO3 : CO21:10 Chronic HCO3 : CO23:10 Acute HCO3 : CO22:10 Chronic HCO3 : CO24:10 Diagnosis of Mixed Metabolic Disorders in Patients with Metabolic Acidosis: Anion Gap Not Increased Non-Anion Gap Acidosis Alone Anion Gap = HCO3 Anion Gap Acidosis Alone Anion Gap < HCO3 Mixed Anion Gap Acidosis + Non-Anion Gap Acidosis Anion Gap > ?HCO3 Mixed Anion Gap Acidosis + Metabolic Alkalosis

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