THROMBOCYTOPENIA

THROMBOCYTOPENIA Low Platelet Count Decreased Production Decreased Megakaryopoiesis • Marrow displacement (e.g. Leukemia, lymphoma, neuroblastoma, other tumour*) • Marrow Failure (e.g. Aplastic Anemia) • Toxic Damage (e.g. Chemotherapy) Ineffective Megakaryopoiesis • B12 Deficiency • Folate Deficiency • Drugs Increased Sequestration • Splenomegaly • Thrombus Increased Destruction Immune • Immune Thrombocytopenia Purpura • Lupus • Alloimmune destruction • Drugs Non-Immune • Hemolytic Uremic Syndrome • Thrombotic Thrombocytopenia Purpura • Disseminated Intravascular coagulation • Infection/sepsis* • Foreign Surface (e.g. Prosthetic Heart Valve) Indicates Key Condition This is not an exhaustive list of medical conditions.