Skin Lesion Primary Skin Lesion Initial lesion not altered by trauma, manipulation (rubbing, scratching), complication (infection), or natural regression over time. Secondary Skin Lesion Lesion that develops from trauma, manipulation (rubbing, scratching), complication (infection) of initial lesion, or develops naturally over time. Types of Lesions Flat Macule (≤ 1 cm diameter) Patch (> 1 cm diameter) Elevated Solid No Deep Component Papule (≤ 1 cm diameter) Plaque (> 1 cm diameter) Firm/Edematous Wheals/Hives Deep Component Nodule (1–3 cm diameter) Tumor (> 3 cm diameter) Transient/Itchy Fluid-Filled OR Semi-Solid-Filled Cyst Purulent Pustule Fluid-Filled (Non-Purulent) Vesicle (≤ 1 cm diameter) Bulla (> 1 cm diameter)

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