Skin Rash Eczematous Papulosquamous Vesiculobullous Pustular Reactive Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated Erythematous or violaceous papules & plaques with overlying scale Blisters containing nonpurulent fluid Blisters containing purulent fluid Reactive rash with various morphology *Indicates Key Condition This is not an exhaustive list of medical conditions. Urticaria Erythema Nodosum Purpura Erythema Multiforme Tender or painful red nodules on shins Target lesions possibly with macules, papules, vesicles &/or bullae on palms soles and mucous membranes Deep red or purple, nonblanchable markings Firm,/edematous papules & plaques that are transient & itchy. Usually lasts <24hrs • Trauma* • Physical abuse* • Thrombocytopenia (Eg. Immune thrombocytopenia purpura*, leukemia*, etc) • Hemophilia* • Allergy/anaphylaxis* • Drug eruption* • Viral induced urticaria Ecchymosis Variable pattern and color • Meningococcemia* • Henoch Schonlein Purpura* • Immune thrombocytopenia purpura* • Inflammatory Bowel Disease* • Other autoimmune conditions • Drug eruption* • Post infectious reaction • Stevens Johnson Syndrome Rash: Clinical Approach to rash – Reactive Author: The Calgary Blackbook, 10th edition Adapted for Paediatrics by: Dr. Theresa Wu

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