PROTEINURIA

Proteinuria See “Edema: Clinical approach to Hematuria” Glomerular Proteinuria Primary Secondary Transient Proteinuria Orthostatic Proteinuria • Exercise • Fever Tubular Proteinuria Glomerular Proteinuria •Genetic/Metabolic disease* (Eg. Renal Fanconi’s, Wilsons disease) •Drugs •Heavy metals •Nutritional •Minimal Change Disease •Focal Segmental Glomerular Sclerosis •Membranous Nephropathy •Mesangioproliferative Glomerulonephritis •Genetic •Infection (Hepatitis virus , HIV, Malaria, Syphillis) •Drugs (Penicillamin, NSAIDs) •Immune/Allergic disorders (Bee sting, Food allergies) •Malignancy (Lymphoma, Leukemia) •Diabetic nephropathy Persistent Proteinuria Primary Secondary Edema: Clinical approach to Proteinuria Author: Dr. Theresa Wu Reviewer: Dr. Carrah Bouma *Indicates Key Condition This is not an exhaustive list of medical conditions. Repeat testing Urine dip negative, but tubular proteins present (Alpha 1 microglobulin). May have Glucosuria, aminoaciduria, acidosis Urine dip positive = albuminuria Active Sediment: RBC cells and casts, WBC casts Urine Microscopy Benign Sediment Negative First morning urine x 3 •UTI* • Dehydration*