MICROCYTIC ANEMIA

Microcytic Anemia Reduced dietary intake (over consumption of cow’s milk) Malabsorption (Eg. Celiac disease*, Inflammatory Bowel Disease*) Chronic Blood Loss β-Thalassemia Minor β-Thalassemia Major α-Thalassemia 2-3 digene deletion Pallor/Anemia: Approach to Microcytic Anemia Iron Deficiency* Anemia of Chronic Disease Hemoglobinopathies* Chronic inflammation (Eg. Juvenile Idiopathic Arthritis*, Inflammatory Bowel Disease*, Lupus, etc.) Ferritin decreased, serum iron decreased, TIBC increased Fe/TIBC <18% MCV/RBC>13 Ferritin normal/increased, serum iron decreased, TIBC normal/decreased Fe/TIBC >18% Ferritin normal/increased, Serum iron normal, TIBC Normal MCV/RBC<13, +/- basophilic stippling, +/- increased reticulocytes Increased HgbA2 Normal HgbA Increased HgbA2 Increased HgbF No HgbA Increased HgbH, HgbH inclusions in RBC *Indicates Key Condition This is not an exhaustive list of medical conditions.