LONG PT (INR), LONG PTT

Factor Deficiency Inhibitor Long PT (INR), Long PTT Heparin Factor X Factor V Factor II Fibrinogen Congenital Acquired Disseminated Intravascular Coagulation Vitamin K Problem Liver Disease Notes: PT more sensitive to Vitamin K deficiency; therefore DPT used for monitoring Coumadin therapy (PTT only affected in very severe cases) PTT more sensitive to heparin; therefore PTT used for monitoring heparin therapy (PT only affected in very severe cases) Bleeding/Bruising Approach to Disorders of Coagulation Vitamin K deficiency * Vitamin K antagonist (Eg. Coumadin) *Indicates Key Condition This is not an exhaustive list of medical conditions.