LONG PT (INR), LONG PTT

Long PT (INR), Long PTT 1. Factor Deficiency → Congenital Factor X deficiency Factor V deficiency Factor II deficiency Fibrinogen deficiency → Acquired Disseminated Intravascular Coagulation Vitamin K Problem: Vitamin K deficiency Vitamin K antagonist (e.g., Coumadin) Liver Disease 2. Inhibitor Heparin Notes: PT is more sensitive to Vitamin K deficiency → PT used for monitoring Coumadin therapy (PTT only affected in very severe cases) PTT is more sensitive to Heparin → PTT used for monitoring Heparin therapy (PT only affected in very severe cases) Indicates Key Condition This is not an exhaustive list of medical conditions.