HYPTONIC INFANT (Floppy Newborn)

Hypotonic Infant* Neurological Upper Motor Neuron ↓ LOC ↓/normal strength Normal reflexes Brain Causes Chromosomal (e.g., Trisomy 21) Genetic (e.g., Prader Willi) Head injury* / Birth trauma* Hypoxic-Ischemic Encephalopathy Intracranial Hemorrhage Intracranial infection (e.g., Meningitis, Encephalitis) ↑ Intracranial pressure* Congenital intracranial structural anomalies Benign congenital hypotonia Lower Motor Neuron Profound weakness Muscle atrophy Fasciculations Absent reflexes Causes Anterior Horn Cell Spinal muscular atrophy Trauma Hematoma Abscess Nerves Hereditary sensory autonomic neuropathy Guillain-Barré syndrome Systemic Illness Sepsis Metabolic disease Hypoglycemia Hypothyroidism Symptoms Weakness (proximal > distal) ↓ Reflexes Muscle atrophy