HEMATURIA

Hematuria Extraglomerular Glomerular IgA nephropathy* Thin basement membrane Alports Benign Familial Hematuria Henoch Schonlein Purpura* Hematuria with Active Sediment Myoglobin (Eg. Rhabdomyolysis) Non-urinary sources of blood (Eg. menstruation, hematochezia) Dyes (Eg. Beets, food coloring) Drugs (Eg. Nitrofurantoin, Rifampin) Vascular (Thrombosis, vascular malformations) Nutcracker syndrome Infectious (Pyelonephritis*, UTI* ) Traumatic (Perineal irritation, vulvovaginitis*, trauma) Neoplasm (Wilms Tumor* ) Renal calculi/hypercalciuria Sickle cell disease Bleeding diathesis (Eg. Hemophilia*, Immune Thrombocytopenia Purpura*) Antibody-mediated (anti-GBM antibodies) Anti GBM/ Goodpastures Pauci-immune (+ANCA) Granulomatosis with polyangiitis Polyarteritis Nodosa Henoch Schonlein Purpura* Hemolytic Uremic Syndrome* Isolated Hematuria with Benign Sediment Urinalysis Urine microscopy Red/pink urine, isomorphic RBC, no casts, no protein Brown urine, dysmorphic RBCs, casts, proteinuria Exclude other causes of red urine *Indicates Key Condition This is not an exhaustive list of medical conditions. Immune Complex mediated Post-infectious glomerulonephritis* Membranoproliferative glomerulonephritis Lupus nephritis Normal/high C3 Low C3 C3