Bleeding/Bruising Initial Tests: CBC, INR, PTT 1. Platelets History of mucosal bleeding, petechiae, bruising on exam ↓ Platelets Normal INR/PTT → Thrombocytopenia See: Bleed and Bruising: Approach to Thrombocytopenia → Disordered Platelet Function Congenital disorders of platelet function Drugs (e.g., ibuprofen, aspirin) 2. Vascular System Normal Platelets Normal INR/PTT → Causes: Connective tissue disorders Inflammatory/vasculitis Drugs 3. Disorders of Coagulation History of prolonged bleeding or hemarthrosis Positive family history Normal Platelets ↑ INR and/or PTT → See: Bleed and Bruising: Approach to Disorders of Coagulation Notes: Indicates Key Condition This is not an exhaustive list of medical conditions

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