ANEMIA BY MECHANISM

Anemia Blood Loss Normocytic, normochromic RBCs Increased reticulocytes If chronic may have: Decreased Reticulocytes, MCV, MCH, MCHC, Serum Iron, Ferritin Increased TIBC, Hypochromic RBCs Types: Acute bleed Chronic bleed Decreased RBC Production Normocytic, normochromic RBCs Normal/Decreased Reticulocytes May have other cell lines down Causes: Iron Deficiency Leukemia B12/Folate Deficiency Aplastic Anemia Anemia of Chronic Disease Hemolysis/Increased RBC Destruction* Increased Reticulocytes Increased Unconjugated Bilirubin Decreased haptoglobin Increased LDH Spherocytes on Smear Types: Congenital Hemoglobinopathies Thalassemia RBC Membrane Disorder RBC Metabolism Disorder Acquired Immune Non-Immune Consumption/Sequestration Normocytic, normochromic RBCs Increased reticulocytes Causes: Hypersplenism Splenomegaly Thrombus *Indicates Key Condition This is not an exhaustive list of medical conditions.