POLYCYTHEMIA

POLYCYTHEMIA JAK-2 Negative Elevated Erythropoietin Reactive JAK-2 Positive Low/Normal Erythropoietin, O2 Saturation >= 90%,Splenomegaly, Increased PMNs Polycythemia (Erythrocytosis) Relative Normal RBC Mass/ Decreased Plasma Volume True Elevated RBC Mass Erythropoietin Secreting TumorO2 O2 Saturation >= 90%Abnormal Abdominal Ultrasound Hypoxia O2 saturation <= 90% High Affinity Hemoglobin O2 O2 Saturation >= 90% Increased carboxyhemoglobin Abnormal P450 determination Smoking, positive Family History,early onset Polycythemia Vera Congenital Hemoglobinopathy Familial Polycythemia Carboxyhemoglobin Heart Murmur, Cyanosis withoutPulmonary Disease Abnormal Chest X-Ray Shortness of Breath, Cough,Smoking, Snoring Chronic Chest Symptoms Cyanotic Heart Disease Sleep Apnea Chronic Pulmonary Disease Burns Diarrhea Dehydration Idiopathic