Overall Approach to Anemia

OVERALL APPROACH TO ANEMIA Increased RBC Destruction Increased Reticulocytes, Increased Unconjugated Bilirubin, Spherocytes on Smear Anemia Iron Deficiency B12/Folate Deficiency Aplastic Anemia Anemia of Chronic Disease Marrow Infiltration Acute Bleed Immune Non-Immune Hemoglobinopathy Thalassemia RBC Membrane II Disorder RBC Metabolism II Disorder Blood Loss Decreased RBC Production Normal/Decreased Reticulocytes Any combination of: Decreased Reticulocytes, MCV, MCH, MCHC, Serum Iron, Ferritin IncreasedTIBC, Hypochromic RBCs Normocytic/Normochromic RBCs on Smear Congenital Acquired Chronic Bleed