APPROACH TO ANEMIA: Mean Corpuscular Volume

Approach to Anemia Mean Corpuscular Volume Anemia Low Mean Corpuscular Volume (<80 fL) Iron Deficiency Thalassemia Lead Poisoning Anemia of Chronic Disease Sideroblastic Anemia Normal Mean Corpuscular Volume (80-100 fL) Bleeding Hemolysis Marrow Failure Anemia of Chronic Disease (e.g., Renal Disease, Liver Disease, Endocrinopathy, Chronic Inflammation, Chronic Infection, Multiple Myeloma) High Mean Corpuscular Volume (>100 fL) B12 Deficiency Folate Deficiency Drugs Reticulocytosis Liver Disease Hypothyroidism Myelodysplasia