ANEMIA WITH ELEVATED MCV

ANEMIA WITH ELEVATED MCV Rule out Reticulocytosis Normal Blood Smear Anemia with elevated Mean Corpuscular Volume (MCV) Anti-IF Antibodies Not Present Drugs Pernicious Anemia Small Bowel Disorder Pancreatic Disease Parasites Pernicious Anemia Oval Macrocytes Hypersegmented Neutrophils RBCs in Rouleaux Formation Dysplastic Macrocytosis Target Cells Normal WBCs Low RBC Folate Low Serum B12 Antibody Testing Dietary Deficiency Malabsorption Increased Requirement ( (e.g. Pregnancy) Anti-IF Antibodies Present Multiple Myeloma Myelodysplastic SyndromesNormal Liver Function Tests Abnormal Liver Function Tests Rule out B12 and Folate Deficiency Liver Disease