MORPHOLOGY OF SKIN LESIONS: Primary Skin Lesions Skin Lesion Macule (<= 1 cm diameter) Patch (> 1 cm diameter) Secondary Skin LesionLesion that develops from trauma, manipulation (rubbing, scratching), complication (infection) of initial lesion, or develops naturally over time Primary Skin Lesion Initial lesion not altered by trauma, manipulation (rubbing, scratching), complication (infection), or natural regression over time. Elevated Flat Fluid-Filled OR Semi-Solid-Filled Solid Fluid-Filled No Deep Component Deep Component Purulent Non-Purulent Fluid Firm/Edematous Transient/Itchy Cyst Papule (<= 1 cm diameter) Plaque (> 1 cm diameter) Nodule (1-3 cm diameter) Tumor (> 3 cm diameter) Vesicle (<= 1 cm diameter) Bulla (> 1 cm diameter) Pustule Wheals/Hives

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