Localized Lymphadenopathy
Inflammatory
Reactive
Neoplastic
• Allergy
• Acne
• Insect bites
• Bacterial (eg.
Pharyngitis, Cellulitis,
Lymphadenitis)
• Non-Hodgkin’s 
Lymphoma
• Hodgkin’s Lymphoma
• Nasopharyngeal
• Head/Neck
• Thyroid
• Breast
• GI Tract
• Melanoma
Infectious
Metastatic 
Carcinoma
Stage I-II 
Lymphoma
Cervical Supraclavicular Axillary Epitrochlear
(Always pathological)
Inguinal
Anterior
• Infection (eg.
Mononucleosis, 
Toxoplasmosis)
Posterior
• TB
• Lymphoma
• Kikuchi Disease
• Head/Neck 
Malignancy
• Thoracic 
Malignancy 
(Breast, 
Mediastinum, 
Lungs, Esophagus)
• Abdominal 
Malignancy 
(Virchow’s Node)
• Infection (Arm, 
Thoracic Wall, 
Breast)
• Cancer (In 
absence of 
infection in upper 
extremity)
• Infection 
(Forearm/Hand)
• Lymphoma
• Sarcoidosis
• Tularemia
• Secondary Syphilis
• Leg Infection
• Sexually 
Transmitted 
Infection
• Cancer